Carla Caccia Selected Research

safinamide

8/2021	The role of glutamatergic neurotransmission in the motor and non-motor symptoms in Parkinson's disease: Clinical cases and a review of the literature.
1/2020	Effects of safinamide on the glutamatergic striatal network in experimental Parkinson's disease.
1/2020	Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo.
1/2020	Safinamide inhibits in vivo glutamate release in a rat model of Parkinson's disease.
1/2018	Safinamide Differentially Modulates In Vivo Glutamate and GABA Release in the Rat Hippocampus and Basal Ganglia.

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Carla Caccia Research Topics

Disease

5	Parkinson Disease (Parkinson's Disease) 01/2020 - 07/2004
3	Dyskinesias (Dyskinesia) 08/2021 - 01/2020
2	Hypertension (High Blood Pressure) 11/2012 - 01/2010
2	Weight Loss (Weight Reduction) 11/2012 - 01/2010
1	Pain (Aches) 08/2021
1	Mood Disorders (Mood Disorder) 08/2021
1	Epilepsy (Aura) 01/2020
1	Myotonia 01/2020
1	Parkinsonian Disorders (Parkinsonism) 01/2020
1	Isolated Systolic Hypertension 01/2010
1	Overweight 01/2010
1	Prehypertension 01/2010

Drug/Important Bio-Agent (IBA)

5	safinamideIBA 08/2021 - 01/2018
4	Levodopa (L Dopa)FDA LinkGeneric 08/2021 - 01/2018
2	Dopamine (Intropin)FDA LinkGeneric 08/2021 - 07/2004
2	Glutamic Acid (Glutamate)FDA Link 01/2020 - 01/2020
2	Sodium Channel BlockersIBA 01/2020 - 01/2020
2	Monoamine Oxidase (MAO)IBA 01/2020 - 07/2004
1	Voltage-Gated Sodium ChannelsIBA 01/2020
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2020
1	Haloperidol (Haldol)FDA LinkGeneric 01/2020
1	Mexiletine (Mexitil)FDA LinkGeneric 01/2020
1	Antipsychotic Agents (Antipsychotics)IBA 01/2020
1	Sodium Channels (Sodium Channel)IBA 01/2020
1	Oxidopamine (6 Hydroxydopamine)IBA 01/2020
1	rasagiline (Azilect)FDA Link 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2010

Therapy/Procedure

3	Therapeutics 08/2021 - 01/2018
2	Dietary Approaches To Stop Hypertension 11/2012 - 01/2010